Clinical Case Orientation: Gastrointestinal and Renal Physiology covers Gastrointestinal and Renal Physiology in undergraduate medical education which needs to be recalled for application in clinical sessions. Clinical cases are presented to take the reader to bench side and challenge them to recall the interplay of physiological aspects with identifying learning objectives. Each case has sequential study questions and answers, multiple choice questions (MCQs), narrative figures and flow charts followed by the key points labelled as “Physiology Pearls”. After reading this book, educators can practice and design clinical cases discussion to facilitate reasoning and memory retention strategies in students. Undergraduate students may use this book as a scaffold for long-term memory retention in the topic of endocrine and reproductive Physiology and Pathophysiology.