COMPUTATIONAL APPROACHES TO PROTEIN DYNAMICS: FROM QUANTUM TO COARSE-GRAINED METHODS

Features • Focuses on the dynamical aspects of biological functions with a special emphasis on IDPs and complex assemblies • Describes the methods and results of enzyme catalysis, including the work of the 2013 Nobel Prize co-winner in chemistry Arieh Warshel • Explains how to apply computational techniques to tackle biological problems involving IDPs • Discusses the experimental characterization of IDPs • Gives a historical overview and description of major directions for improving biological simulations Summary The Latest Developments on the Role of Dynamics in Protein Functions Computational Approaches to Protein Dynamics: From Quantum to Coarse-Grained Methods presents modern biomolecular computational techniques that address protein flexibility/dynamics at all levels of theory. An international contingent of leading researchers in chemistry, physics, and biology show how these advanced methods provide insights into dynamic aspects of biochemical processes. A particular focus is o