HANDBOOK OF METHODS FOR DESIGNING, MONITORING, AND ANALYZING DOSE-FINDING TRIALS
2 in stock
Features Provides an overview of most up-to-date statistical methods required for design, monitoring, and analysis for dose-finding Focuses on the clinical aspects as well as statistical considerations Serves as a reference text for statistical methods for dose-finding trials Can be used as a textbook for a general graduate course that covers broadly statistical methods for dose-finding trials Summary Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of early phase studies. The need to accelerate drug development in a rapidly evolving context of targeted therapies, immunotherapy, combination treatments, and complex group structures has provided the stimulus to these advances.