PATIENT-DERIVED XENOGRAFT MODELS OF HUMAN CANCER

Provides a comprehensive, state-of-the-art review of PDX cancer models written by world-renowned experts in the field Provides interactivity through extensive illustrations This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models are reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current applications are summarized and new perspectives about the use of PDX models are proposed. Each chapter is written by a world-renowned expert who is conducting cutting-edge research in the field. Each of the subsections provides a comprehensive review of existing literature addressing the particular topic followed by a conclusive paragraph detailing future directions.