THE LUNG: DEVELOPMENT MORPHOGENESIS MECHANBIOLOGY AND STEM CELLS

With a detailed scientific background and up-to-date research, this book examines recent developmental and cell biology, mechanobiology, and stem cell biology discoveries to help provide a better understanding of lung development, repair, and regeneration. Lung regeneration is an urgent therapeutic priority. The current major challenge is the generation of complex vascularized structures that can ultimately support or replace impaired lung function. Recent discoveries in biomedical engineering are analyzed within the structural context of the lung to help provide a better understanding of the innovative solutions that could be used for restoring normal morphogenesis and regeneration of the lung. This also includes insights from basic developmental mechanisms of human lung development through the derivation and identification of stem cells, both from the early embryo as well as from differentiated organs and tissues.